Here's Why Nattokinase Is the Secret to Healthy Cardiovascular Function & Circulation
SUPPORT YOUR HEART HEALTH
"Since using Nattokinase daily, I feel more energized, focused, and just overall better. I'm committed to the full 12 months."
"My doctor recommended I look into nattokinase. Three months of consistent use and I genuinely feel the difference in my daily energy."
"I subscribed 6 months ago and haven't looked back. I feel sharper, more energized, and my overall sense of well-being has never been better."
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Why Even 1% Less Plaque Changes Everything
A major 2023 study combined 23 clinical trials and over 7,400 patients. The results were striking β even tiny reductions in artery plaque led to dramatically fewer heart events.
Just 1% plaque shrinkage reduced the risk of heart attack, stroke, or cardiovascular death by up to 25%
Based on meta-analysis of 23 clinical trialsRisk Reduction From Plaque Regression
It's Not Just Smaller β It's Safer
When plaque shrinks, it doesn't just get a little smaller. It transforms from a dangerous, unstable mass into a firm, calcified cap β and that distinction is everything.
Unstable plaque has a thin, fragile outer layer. When it ruptures, your body reacts the same way it does to a wound β it forms a blood clot. But inside an artery, that clot can block blood flow entirely. If it happens in the heart, it's a heart attack. In the brain, a stroke. This is how the majority of cardiac events actually occur β not from arteries slowly closing, but from plaque suddenly breaking open.
Even a small reduction in plaque volume stabilises the remaining plaque, thickening that protective cap and dramatically lowering the chance of rupture.
Research Shows Nattokinase May Support Healthier Arteries
A 12-month clinical study of 1,062 participants examined nattokinase's role in supporting cardiovascular health. Here's what the researchers observed.
Researchers Observed Positive Changes in Artery Health
After 12 months, researchers measured both plaque size and artery wall thickness using ultrasound imaging.
The carotid artery supplies blood to the brain. These measurements are commonly used by researchers to assess cardiovascular wellness.
Participants Showed Improvements in Key Lipid Markers
The majority of participants showed positive changes in lipid markers after 12 months of nattokinase supplementation at 10,800 FU/day.
% of study participants who showed improvement*
What Is Nattokinase?
Nattokinase is a natural enzyme produced during the fermentation of soybeans into natto β a traditional Japanese food eaten for over 1,000 years. Japan has the second-highest life expectancy in the world, and areas where people eat the most natto consistently show lower rates of heart disease and stroke.
The enzyme was first discovered by Japanese researcher Dr. Hiroyuki Sumi in 1987, and has since become one of the most studied natural heart-health compounds in the world. It works by breaking down fibrin β the protein that holds blood clots together and keeps plaque stuck to your artery walls. Nattokinase dissolves that "glue." It also boosts your body's own clot-dissolving enzymes β so your arteries can stay cleaner on their own.
Think of it like this: if plaque is the buildup clogging your pipes, nattokinase is the enzyme that loosens and breaks it apart β naturally, safely, and without the side effects of prescription drugs.
Nattokinase β the enzyme extracted from natto
"But Where Does the Plaque Go?"
This is one of the most common questions people ask β and the answer is simple. When nattokinase breaks down fibrin and loosens plaque from your artery walls, those tiny fragments enter your bloodstream as microscopic particles. Your body's built-in filtration system takes care of the rest β your liver processes and neutralises the debris, and your kidneys filter it out through urine. It's the same system your body already uses every day to clean your blood β nattokinase just gives it more to work with.
Nattokinase Works on Three Fronts
Breaks Down Fibrin
Fibrin is the protein that holds blood clots together and keeps plaque glued to your artery walls. Nattokinase directly dissolves fibrin β which is what makes it different from almost every other natural supplement out there.
Helps Your Body Fight Clots
Your body already makes its own clot-dissolving enzyme called t-PA. Nattokinase boosts t-PA production and reduces PAI-1 β the protein that blocks it. The result? Your body gets better at clearing dangerous clots on its own.
Supports Healthy Blood Pressure
Clinical studies show nattokinase can lower both systolic and diastolic blood pressure. Better blood flow means less strain on your heart, your brain, and every organ in your body.
Not All Supplements Are Created Equal
Most heart-health supplements on the market are stuffed with cheap synthetic vitamins, manufactured overseas with no clinical backing. Ours is different.
What To Expect From Consistent Use
Nattokinase works gradually to support your body's natural processes. Here's what the research suggests may happen when you commit to daily supplementation over 12 months.β
"The Journey Begins"
This is your starting point. Nattokinase enters the bloodstream within hours and begins supporting your body's natural fibrinolytic processes β the system responsible for maintaining healthy fibrin levels. Like any meaningful nutritional support, consistent daily use is key to experiencing the full benefits.β
The "Foundation" Phase β Trust the Process
Let's be honest β you probably won't feel any different during this phase. That's completely normal, and it's not a reason to stop. Behind the scenes, nattokinase is actively supporting your body's natural fibrin metabolism and helping maintain cardiovascular function already within the normal range. Your body is building the foundation for the benefits ahead.β
Talk to your healthcare provider about baseline wellness markers. Routine bloodwork can help you track changes in markers like lipid levels over time and understand how your body is responding to supplementation.β
Consider baseline bloodwork with your healthcare provider
Building Momentum β Supporting Healthy Fibrin Metabolism
This is where months of consistency start to matter. Nattokinase continues to support your body's natural enzyme activity involved in healthy fibrin metabolism. Some users report noticing improvements in how they feel during daily activities β such as a general sense of vitality and well-being. Individual results may vary.β
Supporting the body's natural enzyme processes
Sustained Cardiovascular Support
Months of consistent nattokinase supplementation are now providing ongoing support for your cardiovascular system. Users often report a greater sense of overall well-being, including feeling more energized during everyday activities. Healthy circulation and normal fibrin levels support the body's natural functions across the board. Stay consistent.β
Ongoing cardiovascular support
The Full Commitment β Long-Term Cardiovascular Support
This is why you committed to 12 months. Published research on nattokinase supplementation suggests that long-term, consistent use supports healthy cardiovascular function, including maintaining healthy circulation and supporting the body's normal fibrin metabolism. Twelve months of daily consistency gives your body the sustained nutritional support it needs.β
Follow up with your healthcare provider. Routine wellness bloodwork can help you and your provider understand how your overall wellness markers have responded over time.β
Long-term cardiovascular support through consistent useMeaningful Cardiovascular Support Takes Consistency
Let's be real β if you buy one bottle, take it for a month, and don't notice anything different, you'll probably stop. And that's exactly the problem. The research on nattokinase suggests that long-term, consistent daily use is what makes the difference. Like many nutritional strategies, the benefits of nattokinase are cumulative and build over time.β
That's why we recommend subscribing. It removes the friction β your next bottle arrives before you run out, you never break the chain, and you give your body the full 12 months of consistent support. One bottle is an expense. Twelve months is a commitment to your well-being.
Every Batch. Tested. Every Result. Published.
Most supplement brands ask you to trust them. We'd rather just show you the proof. Every single batch of our nattokinase is independently tested by third-party labs β and we publish every result online for anyone to see.
How It Works
What Every Batch Is Tested For
219 Clinicians Recommend Our Nattokinase
Without compensation. Without sponsorship. Without being asked. They recommend it because it works.
That's why I recommend Nattokinase Artery Support β it helps maintain healthy circulation by breaking down blood clots and supporting the body's natural ability to cleanse arteries by targeting fatty plaque buildup.
Join 100,000+ Just Like You Supporting Heart Health Naturally
Nattokinase Capsules - 5000 FU
Nattokinase Capsules - 5000 FU
Nattokinase is a natural enzyme from fermented soybeans that is taken as a supplement to support cardiovascular health by helping break down blood clots.
- For Cardiovascular Health*
- Increases Elasticity & Strength Of Artery Walls*
- Strengthens Blood Vessels*
- Improves Function Of The Heart*
As Seen On
Questions? We've got you covered!
Nattokinase is a serine protease enzyme (not actually a "kinase" despite its name) produced byΒ Bacillus subtilis nattoΒ during the fermentation of soybeans intoΒ natto, a traditional Japanese food. It is best known for itsΒ fibrinolytic activityΒ β its ability to break down fibrin, the protein involved in forming blood clots.
Research suggests nattokinase may support cardiovascular health in several ways, including supporting healthy blood pressure levels, improving circulation and blood flow, helping prevent and break down blood clots, supporting arterial flexibility, and inhibiting platelet aggregation. Early research also hints at potential benefits for brain health.
Natural Foundation offers nattokinase in two research-backed dosages:5,000 FUand10,000 FU. These dosages are grounded in scientific research. A clinical study of 1,062 participants published in Frontiers in Cardiovascular Medicine found that nattokinase supplementation at10,800 FU/day for 12 months led to a36% reduction in arterial plaque sizeand significant improvements in cholesterol markers. Additional studies have shown that dosages in the range of2,000β7,000 FU/day support healthy blood pressure, improved blood flow, and clot prevention. Natural Foundation's dosages are designed to give you flexibility β whether you're looking for daily cardiovascular maintenance (5,000 FU) or more targeted support (10,000 FU).
The first reason we took it out is because a lot of people already take Vitamin K with their Vitamin D. So they were getting a double dose and we had a good number of customers complain. Another reason is that Nattokinase is a blood thinner, and Vitamin K is a clotting agent. Vitamin K is essential for making several proteins (like prothrombin) that help your blood clot properly when you get injured. So in that sense it's a bit counterproductive. One does one thing and the other does the opposite. Vitamin K is great for arteries, though, we just didn't think it made sense to have it in the same supplement. We chose to take it out knowing that vitamin D3 K2 is a very affordable supplement and those who want to take it alongside easily can. Motherwort and Oregano also have good benefits for the heart and arteries. It's one of those situations where we can only keep so many people happy...
If you're taking medication, it's best to consult your healthcare provider before adding any supplement.
We dispatch all orders the same day or the next working day. Shipping typically takes 1β3 working days, depending on the shipping option you select at checkout.
Our Blood Pressure Support is manufactured in the UK at our certified facility to ensure the highest quality and safety standards.
Nattokinase Artery Support is made from natural ingredients and is generally well-tolerated. However, consult your doctor if you have any pre-existing conditions or concerns.
A 50g serving of natto contains an average of about 1,500 FU of nattokinase. To match Natural Foundation's 5,000 FU dosage through food alone, you'd need to consume roughly 3β4 packs of natto daily β and even more for the 10,000 FU dosage. Nattokinase in supplement form is also less vulnerable to stomach acid than the enzyme found in whole natto. Additionally, natto contains significant vitamin K2, which can interfere with certain medications like warfarin, whereas quality nattokinase supplements typically have vitamin K2 removed.
Why I Built the Supplement Company I Wished Existed
Hey, I'm Logan. I founded Natural Foundation Supplements, and I want to take a second to tell you why this company exists.
I started this company because I was tired of being lied to.
I spent over 20 years dealing with health issues. And when I finally started looking into the supplements I was taking, I found out most of them weren't even close to what was on the label.
Think about that for a second. You go to the shop, you pick up a bottle, you read the label, you trust it. And 8 times out of 10, what's inside doesn't match what's printed on the outside. The dosages are wrong. The active ingredients are missing. And nobody checks, because nobody is required to.
That's not a quality problem. That's a trust problem. And once I saw it, I couldn't unsee it.
So I built the company I wished existed
One that actually puts what it says on the label. One that proves it with independent thirdβparty testing. And one that doesn't hide behind proprietary blends or fancy marketing.
We don't outsource production. We manufacture everything in house, in our own GMPβcertified facility. GMP stands for Good Manufacturing Practice, and it means every step of our process, from raw ingredient intake through to bottling, follows strict quality and hygiene standards. We control the entire chain. Nothing leaves our facility unless we're confident it's exactly what the label says it is.
On top of that, every single batch is sent to an independent laboratory. They test for dosage accuracy, identity verification, heavy metals, and microbiological safety. We don't pick and choose which results to share. We publish all of them, for every product, for every batch. Every bottle ships with a scannable QR code. Scan it, and you'll see the exact test results for your batch. Not a generic certificate. Not a stock photo of a lab. The actual results for the actual bottle in your hand.
Transparency isn't a marketing strategy for us. It's the whole point.
I know you had a thousand options when it came to choosing a supplement. And I know that most companies in this industry are saying roughly the same things: "premium quality," "clinically studied," "trusted by thousands." The words are easy. The proof is what's hard.
That's why we don't ask you to take our word for it. We give you the data and let you decide for yourself.
"I spent 20 years trusting labels that weren't worth the paper they were printed on. I built Natural Foundation so you wouldn't have to do the same."
I also test other brands on camera
I post videos on YouTube where I send popular supplements off for independent thirdβparty testing and share the results publicly. No sponsorships, no filters, just the raw lab data. If you want to see what's really inside the supplements you're buying, search for Logan Talks Health on YouTube.
Thank you for trusting us. I don't take it lightly.
Founder, Natural Foundation Supplements